Maggie is an uptight, single mother and college writing teacher from New York City. In an effort to reconnect with her troubled teen daughter Summer, she decides to embark on a journey to a Tuscan village that she frequented in her younger days. Upon arrival, Maggie runs into Luca, a handsome former lover who is still a bachelor and lives with his eighty-year-old mother, Carmen. Summer (missing her "bad boy" boyfriend in NYC) and Carmen (secretly planning a wedding against Luca's wishes to Marcelino, her one true love in Rome) impulsively steal Luca's car and race off to Rome. Maggie and Luca quickly pursue allowing the two mismatched couples to spend some time together and develop a new understanding of each other.

In Torino, Celine, an American model, is abducted by a taxi driver while en route home to meet her sister Linda, visiting at her apartment. The next morning, Linda reports that Celine is missing - the sergeant in charge directs her to F.B.I. agent Inspector Enzo Avolfi. He's from the Special New York City Department investigating a serial-killer that kidnaps foreigners to destroy their beauty. When a Japanese woman is found at nearby a fountain, Enzo and Linda find that the girl is calling the abductor's skin is "Yellow" in color and Linda concludes that the guy might have jaundice. They go to the Policlinic di Torino to find the killer.

Despite guidance from the Blue Fairy, and the love of his father, Gepetto, a wooden puppet's curious...

In Rome, after the abduction of a British tourist, the police inspector Anna Mari is contacted by the criminal, who self-entitles The Card Player, challenging the police department to dispute a video poker with him where the prize would be the life of the victim. The Chief of Police refuses to participate and the victim is tortured and killed in front of an Internet web cam. The British detective John Brennan is assigned to investigate the case and when another woman is kidnapped, they invite the addicted player Remo to play for the police. Anna and John lead the investigation trying to disclose who might be the serial-killer.